Regulation of Alternative Splicing (Progress in Molecular and Subcellular Biology)
Editorial Reviews
Book Description
The generality and quantitative extent of alternative splicing have only now begun to be fully appreciated. The first draft of the complete human genome led to the surprisingly low figure of about 32,000 genes. The extensive use of alternative splicing and its consequences in terms of coding capacity could account for this discrepancy and help fill the complexity gap between the genome and the proteome. After a computer-based assessment of the frequency of alternative splicing, this book addresses mechanistic aspects followed by examples of its involvement in important cellular processes. Finally, it raises the possibility of artificial modulation of alternative splicing by antisense nucleotides.
Book Info
Institute of Molecular Genetics of Montpellier, France. Text covers the principles of alternate splicing and focuses on the hypothesis that alternative splicing dysregulation may be behind a growing number of diseases. Extensive references with halftone illustrations.
Regulation of Alternative Splicing (Progress in Molecular and Subcellular Biology),Philippe Jeanteur,Springer,3540438335,Exons (Genetics),Genetic recombination,Genetics,Life Sciences - Biochemistry,Life Sciences - Biology - General,Life Sciences - Biology - Molecular Biology,Life Sciences - Genetics & Genomics,Molecular Biology,Molecular Genetics,Science,Science/Mathematics,Split genes,Development,Gene Expression,Genomics,Genomik,RNA,RNS,Science / Biology,Sex Determination,Spleißen,Spleißomon
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