Mechanisms and Mediators of Neuropathic Pain (Progress in Inflammation Research)
Editorial Reviews
Book Description
Numerous improvements in our understanding of the mechanisms that underlie neuropathic pain states have come from the development of animal models, most of which involve partial peripheral nerve injury. The animal models have shown that nerve injury initiates a cascade of events resulting in altered neurochemistry and molecular biology of the peripheral neurons, the dorsal root ganglion cell, and changes in neurotransmitter and receptor expression in the dorsal horn of the spinal cord. Moreover, nerve injury produces anatomical changes with functional consequences. This volume summarises the current understanding of the pathophysiological processes in the peripheral and central nervous system that contribute to the neuropathic pain. It provides a timely review of neuropathic pain mechanisms, written by experts in the field.
Book Info
Summarizes current understanding of the pathophysiological processes in the peripheral and central nervous system contributing to the neuropathic pain. Reviews neuropathic pain mechanisms and focuses on peripheral consequences of nerve injury, spinal cord plasticity, preclinical and clinical paradigms, and new treatments.
Mechanisms and Mediators of Neuropathic Pain (Progress in Inflammation Research),Annika B. Malmberg,Sandra R. Chaplan,Birkhauser,3764362375,Diseases Of Peripheral Nerves,Hyperalgesia,Life Sciences - Biology - General,Medical,Medical / Nursing,Molecular aspects,Neuralgia,Neurology - General,Pathophysiology,Peripheral Nerves,Neurology,Pain Research,Science / Biology
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