Protease Inhibitors in AIDS Therapy (Infectious Disease and Therapy)
Editorial Reviews
Book Description
Details the evolution of HIV protease inhibitors from molecular development through medical applications!Considering the latest class of revolutionary drugs fighting against HIV infection and AIDS, this comprehensive reference thoroughly examines the development and properties of HIV protease inhibitors from clinical and scientific perspectives, discussing how protease inhibitors changed the FDA approval process-enhancing the collaboration between regulatory authorities and drug developers.Spotlights protease inhibitors as the cornerstone drugs of the first HAART regimens-key components of long-term viral suppression and immune restoration, and in secondary and tertiary regimens!Evaluating protease inhibitors as therapeutic options and research tools, Protease Inhibitors in AIDS Therapyreviews the impact of advances in recombinant DNA technology for understanding and treating HIV and AIDShighlights a variety of strategies and techniques for drug discovery and development illustrated by success stories of pharmaceutical companies and biotechnology start-up firmssummarizes the pharmacokinetics, metabolism, and drug interactions of protease inhibitorsdetails preliminary clinical studies on oral bioavailability, pharmacokinetic profiling, efficacy, resistance, and tolerabilitydescribes available efficacy data for marketed inhibitors and those in clinical developmentreports on efforts to manage antiviral resistance in the clinic and improve patient adherence to complex drug therapyand more!Containing more than 600 helpful literature references, drawings, photographs, and tables, Protease Inhibitors in AIDS Therapy serves for an essential reference for infectious disease specialists, epidemiologists, virologists, immunologists, pharmacologists, medicinal chemists and biochemists, microbiologists, hematologists, hepatologists, and medical students in these disciplines.
Book Info
Agouron Pharmaceuticals, Inc., San Diego, CA. Reviews the impact of advances in recombinant DNA technology for understanding and treating HIV and AIDS. Highlights a variety of stories of pharmaceutical companies and biotechnology start-up firms. Reports on efforts to manage antiviral resistance in the clinic.
Protease Inhibitors in AIDS Therapy (Infectious Disease and Therapy),Richard C. Ogden,Charles Flexner,Informa Healthcare,0824704614,AIDS & HIV,AIDS (Disease),Aids (Acquired Immune Deficiency Syndrome),Chemistry - General,Chemotherapy,Enzymology,Infectious Diseases,Life Sciences - Biochemistry,Medical,Medical / Nursing,Pharmacy,Protease inhibitors,HIV / AIDS,Pain & pain management,Pharmacology,Science / Chemistry / General
Books Review:
Recommended Books