Introduction to Systems Biology and the Design Principles of Biological Networks (C&H/Crc Mathematical & Computational Biology Series)
Editorial Reviews
Review
...Beyond simply recounting recent results, Alon boldly articulates the basic principles underlying biological circuitry at different levels and shows how powerful they can be in understanding the complexity of living cells. For anyone who wants to understand how a living cell works, but thought they never would, this book is essential.
Michael B. Elowitz, California Institute of Technology, USA
Uri Alon offers a highly original perspective on Systems Biology, emphasizing the function of certain simple networks that appear as ubiquitous building blocks of living matter. The quest for simplicity - without losing contact with complex reality - is the only way to uncover the principles organizing biological systems. Alon writes with uncommon lucidity…
Boris Shraiman, UCSB, USA
This is a remarkable book that introduces not only a field but a way of thinking. Uri Alon describes in an elegant, simple way how principles such as stability, robustness and optimal design can be used to analyze and understand the evolution and behavior of living organisms. Alon's clear intuitive language and helpful examples offer - even to a mathematically naive reader - deep mathematical insights into biology. The community has been waiting for this book; it was worth the wait.
Galit Lahav, Harvard Medical School, Boston, Massachusetts, USA
Book Description
This book presents recently discovered design principles that govern the structure and behavior of biological networks such as gene circuits, highlighting simple, recurring circuit elements that make up the network. It provides a quantitative theory for which circuits are found in a given environment and a mathematical framework for understanding and even designing biological circuits. The book requires only basic mathematics and includes a review of the necessary background material. It fills a significant need for a textbook and introduction to the concepts, principles, and mathematical tools that will form the basis of future developments in the field.
An Introduction to Systems Biology (C&H/Crc Mathematical & Computational Biology Series),Uri Alon,Chapman & Hall/CRC,1584886420,Applied,Biological systems,Biotechnology,Computational biology,General,Mathematical models,Mathematics,Physics,Probability & Statistics - General,Science,Science/Mathematics,Biology, Life Sciences,Mathematics / Applied
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